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Osmosis Jones is a 2001 American live-action/animated buddy cop action comedy film directed by the Farrelly brothers. Featuring the voices of Chris Rock, Laurence Fishburne, David Hyde Pierce, Brandy Norwood and William Shatner alongside live actors such as Bill Murray, Molly Shannon and Chris Elliott, the film centers on Frank DeTorre, a slovenly zookeeper who contracts a deadly virus known as Thrax; the live-action sequences are set outside Frank’s body while the animated sequences are set inside his body, which is depicted as a city inhabited by anthropomorphic parameciums.
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